One of the most important aspects of the INBRE is the mentoring of eight promising new investigators in their research project endeavors. Mentoring will be an ongoing team effort including the designated project mentors, but also the INBRE Principal Investigator, the Steering Committee and the External Advisory Committee. These research projects will be supported for 2˝ years.
Current Junior Investigator Awards
Non-invasive Neuromodulation to Suppress Atrial Fibrillation
Dr. Stavros Stavrakis
University of Oklahoma Health Sciences Center
Roles of microRNA in Central Nervous System Infection
Dr. Douglas Drevets
University of Oklahoma Health Sciences Center
The Role of SOD-1 in Docosahexaenoic Acid-induced Cytotoxicity in Cancer Cells
Dr. Wei-Qun Ding
University of Oklahoma Health Sciences Center
Mentor: Dr. Doris Benbrook, University of Oklahoma Health Sciences Center
Cyclen Based Novel Antimalarial Agents
Dr. Faruk Khan
Southwestern Oklahoma State University
Mentor: Dr. Daniel Carr, University of Oklahoma Health Sciences Center
Applications of Novel Marine Fungal Siderophores
Dr. Jessica Martin
Northeastern State University
Mentor: Dr. Jimmy Ballard, University of Oklahoma Health Sciences Center
Autonomic and microvascular functions and pressure ulcers in spinal cord injury
Dr. Yih-Kuen Jan
University of Oklahoma Health Sciences Center
Mentor: Dr. Robert Foreman, University of Oklahoma Health Sciences Center
Arsenic exposure and gestational diabetes
Dr. Jennifer Peck
University of Oklahoma Health Sciences Center
Mentor: Dr. Julie Stoner, University of Oklahoma Health Sciences Center
TopBP1 complexes in DNA replication and the chemotherapy response
Dr. Christopher Sansam
Oklahoma Medical Research Foundation
Mentor: Dr. Gary Gorbsky, Oklahoma Medical Research Foundation
Low cost clot-dissolving protein from transgenic plants for stroke treatment
Dr. Yueju Wang
Northeastern State University
Mentor: Dr. William Hildebrand, University of Oklahoma Health Sciences Center
An intelligent system for clinical guidance on power seat function usage
Dr. Jicheng Fu
University of Central Oklahoma
Mentor: Dr. David Dyer, University of Oklahoma Health Sciences Center
HISTORY OF OK-INBRE MINI, COLLABORATIVE, EQUIPMENT AND RELEASE TIME GRANTS
| Arden | Aspedon | SWOSU | 2002 | mini grant | Identification of Molecular Genetic Determinants Mediating Peptide Resistance and Osmoadaptation in Pseudomonas aeruginosa | |
| John | de Banzie | NSU | 2002 | mini grant | Assessment of Method to Map Nuclear Architecture | |
| Jason | Johnson | SWOSU | 2002 | mini grant | Establishing Fluorescence Systems for Analyzing Allosteric and Oligomerization Mechanisms in E coli Carbamoyl Phosphate Synthetase | |
| Bill | Kelly | SWOSU | 2002 | mini grant | Theoretical Assessment of Carotenoid Antioxidant Activity: Can Theoretical Calculations of Thermodynamic Parameters Provide a Quantitative Correlation of Carotenoid Radical Scavenging Activity | |
| Kathi | McDowell | NSU | 2002 | mini grant | Construction and Analysis of Segments of the Ribosomal DNA Repeat Unit Potentially Responsible for Nucleolar Formation in Human Cell Lines | |
| Sonya | Williams | LU | 2002 | mini grant | Age Related Loss of Estrogen Affects Cerebellar Macrophages | |
| KJ | Abraham | LU | 2003 | mini grant | Molecular Screening of Human Intestinal Bacteria for the Presence of Azoreductase Gene | |
| Arden | Aspedon | SWOSU | 2003 | mini grant | Identification and Characterization of Molecular Genetic Determinants Mediating Osmoadaptation in Pseudomonas aeruginosa | |
| Jason | Johnson | SWOSU | 2003 | mini grant | Probing Allosteric Interactions within E. coli Carbamoyl Phosphate Synthetase via Intrinsic Fluorophores | |
| Bill | Kelly | SWOSU | 2003 | mini grant | Assesing Carotenoid Antioxidant Activities by Computational Methods: Can Theoretically Determined Ionization Potentials and Bond Dissociation Energies Shed Light on The Mechanism of Superoxide Radical Quenching | |
| Monica | Macklin | NSU | 2003 | mini grant | Determination of Phylloquinone Levels in Wild-harvested Native Plants and the Dietary Usse of Wild-harvested Plants by Older Native Americans | |
| Kathi | McDowell | NSU | 2003 | mini grant | Investigation of Transcriptional Activity and Nucleolar Participation from Plasmids Containing Partial Human rDNA Transcriptional Units Transiently Transfected into a Human Cell Line | |
| Sonya | Williams | LU | 2003 | mini grant | Estrogen as a Gatekeeper of Cytokine Expression by Microglia | |
| KJ | Abraham | LU | 2004 | collaborative grant | Development of a Classification Scheme Using a Secondary and Tertiary Amino Acid Analysis of Azoreductase Gene | |
| Arden | Aspedon | SWOSU | 2004 | collaborative grant | Identification of Osmoadaptive Genes in Pseudomonas aeruginosa | |
| David | Chambers | NSU | 2004 | mini grant | Biochemical Analysis of the D. Melanogaster and C. elegans ERM proteins | |
| Bill | Kelly | SWOSU | 2004 | collaborative grant | Is Retinoid Induced Cell Apoptosis Mediated by Superoxide Radical Anion Production | |
| Cindy | Cisar | NSU | 2005 | mini grant | Development of a PCR-based assay for the detection of checken feces | |
| Daniel | Endres | UCO | 2005 | collaborative grant | A Model Bgased Investigation of DNA Microsatellite Repeat Instability at the Friedreich Ataxia Locus | |
| Bill | Kelly | SWOSU | 2005 | collaborative grant | Investigations of SHetA2 Mediated Mitochondria Changes in Human Cncer Organotypic Cultures | |
| Mauricio | Sanchez | UCO | 2005 | mini grant | Three-Dimensional Finite Element and Heat Transfer Modeling of a Cemented Total Hip Arthroplasty | |
| Tim | Smith | SOSU | 2005 | collaborative grant | Carbohydrate Metabolism of e coli | |
| Muatasem | Ubeidat | SWOSU | 2005 | mini grant | Tagging Genes that Affect the Expression of 5'-Nucleotidase in Dictyostelium | |
| Mohamed | Bingabr | UCO | 2006 | mini grant | Improving Speech Intelligibility for Cochlear Implant Users by Selecting Spectral Bands that Minimize the Effect of Noise and Electrode Interaction | |
| David | Chambers | NSU | 2006 | release time | grant writing | |
| John | de Banzie | NSU | 2006 | release time | course development | |
| Daniel | Endres | UCO | 2006 | release time | grant writing | |
| Daniel | Endres | UCO | 2006 | collaborative grant | A Model Based Investigation of DNA Microsatelite Repeat Instability at the Friedreich Ataxia Locus | |
| Anne | Ewing | UCO | 2006 | release time | course development | |
| Dennis | Frisby | CU | 2006 | mini grant | Regulation of Cholinergic Function in Caenorhabditis elegens | |
| Tim | Hubin | SWOSU | 2006 | mini grant | Configurationally Restricted Bis-Azamacrocyles; Chemokine Recepter Antagonists | |
| Yefim | Kats | SWOSU | 2006 | release time | course development | |
| Rick | Matzen | NSU | 2006 | release time | course development | |
| Kathi | McDowell | NSU | 2006 | release time | course development | |
| Mike | Morris | SOSU | 2006 | release time | course development | |
| Christopher | Pritchett | NSU | 2006 | mini grant | The Role of LytR in the Virulence of Mycobacterium marinum | |
| Gang | Qian | UCO | 2006 | mini grant | Bulk-loading and Performance Studies of the ND-Tree of Large Genome Databases | |
| Mauricio | Sanchez | UCO | 2006 | mini grant | Heart Valve Dynamics and of Non-Newtonian Fluid Structure Interactions | |
| James | Schooley | NSU | 2006 | release time | course development | |
| Tim | Smith | SOSU | 2006 | release time | grant writing | |
| Tim | Smith | SOSU | 2006 | collaborative grant | Metabolism Studies of E. Coli | |
| Mary | Song | CU | 2006 | release time | course development | |
| Muatasem | Ubeidat | SWOSU | 2006 | release time | grant writing | |
| Melville | Vaughn | UCO | 2006 | release time | grant writing | |
| Frankie | White | CU | 2006 | collaborative grant | Estradiol and Interleukin-1B Regulate the uterine Inflammatory Response Permitting Establishment of Pregnancy | |
| Donna | Smith | NSU | 2006 | release time | grant writing | |
| Christopher | Pritchett | NSU | 2006 | release time | grant writing | |
| Kathi | McDowell | NSU | 2006 | release time | course development | |
| Christopher | Morretti | SOSU | 2006 | release time | course development | |
| Mike | Morris | SOSU | 2006 | release time | course development | |
| Yefim | Kats | SWOSU | 2006 | release time | course development | |
| Sharon | Lewis | LU | 2006 | release time | grant writing | |
| Rick | Matzen | NSU | 2006 | release time | course development | |
| Melville | Vaughn | UCO | 2006 | release time | grant writing | |
| William | Kelly | SWOSU | 2006 | release time | course development | |
| William | Kelly | SWOSU | 2007 | collaborative grant | Effects of Flex-Hets on Ovarian Cancer Cell Metabolism: Evaluating the Mechanism of NADH: Ubiquinone | |
| Tim | Smith | SOSU | 2007 | collaborative grant | Metobolism Studies of E. coli | |
| Jessica | Martin | NSU | 2007 | mini grant | Iron-binding Compounds Produced by Open Water Marine Fungi | |
| Theresa | Golden | SOSU | 2007 | mini grant | The Role of Protein Phosphatase 5 (PP5) in Cancer | |
| Mohamed | Bingabr | UCO | 2007 | mini grant | Effects of Bipolar and Monopolar Current Spread on Forward Masking and Speech Intelligibility of Cochlear | |
| Gang | Qian | UCO | 2007 | mini grant | Extending Search Ranges of the ND-tree to Support Efficient Bioinformatics Database Queries Using the Edit | |
| Smith | Tim | SOSU | 2008 | collaborative grant | Metabolism Studies of E. coli | |
| Seong | Jaehoon | UCO | 2008 | mini grant | Fabrication of Transparent Silicone Vascular Replicas of Human Carotid Bifurcation | |
| Qian | Gang | UCO | 2008 | mini grant | Supporting Efficient Protein Homology Detection Based on Profile Hidden Markov Models | |
| Thibodeaux | Jeremy | UCO | 2008 | mini grant | Modeling Erythrpoiesis Subject to Malaria Infection: Model Formation, Analysis and Simulation | |
| White | Frankie | UCO | 2008 | mini grant | Estrogen Disruption of Pregnancy Alters Uterine Gene Expression | |
| Lewis | Sharon | LU | 2008 | mini grant | Bioinformatics of Bipolar Disorder | |
| Biles | Charles | ECU | 2008 | mini grant | Chemical and environmental Regulation of Chaetomium Glabosum Vegetative Growth and Reproduction | |
| Linder | Douglas | SWOSU | 2008 | mini grant | Geometric Influences on the Protonation State of Zinc-coordinated Inhibitors in MMPs | |
| Khan | Md | SWOSU | 2008 | mini grant | Synthesis of Isoquinuclidine Analogs of Chloroquine as Potential Antimalarial and Antileishmanial Chemotherapeutic Agents | |
| Andrea | Holgado | SWOSU | 2009 | release time | course development | Cellular biology laboratory |
| Stephen | Fields | ECU | 2009 | release time | course development | TBM - Training Undergraduates n Mathematical Moedling of Population Genetics |
| William | Kelly | SWOSU | 2009 | collaborative grant | Effects of short and long term flex-het therapy on mitochondrial electron-transport function | |
| Wei | Chen | UCO | 2009 | collaborative grant | MRI Guided Photoimmunotherapy | |
| Timothy | Smith | SE | 2009 | mini grant | Explorations of Capillary Electrophoresis in the Analysis of Model Glycoproteins | |
| Daniel | Endres | UCO | 2009 | mini grant | Advanced Stochastic Models for DNA Microsatelite somatic instability | |
| Gang | Qian | UCO | 2009 | mini grant | Incorporating substitution matricies into the NSP-tree for efficient and sensitive pair-wise alignments in large biological sequence databases | |
| Teresa | Golden | SE | 2009 | mini grant | The role of protein phosphatase 5 (PP5) in hypoxic stress and cancer | |
| Andrea | Holgado | SWOSU | 2009 | mini grant | Molecular analysis of vesicle exocytosis | |
| Jason | Johnson | SWOSU | 2009 | mini grant | Unraveling the GTP-mediated coordinatoni of CTP synthetase | |
| Jeremy | Thibodeaux | UCO | 2009 | mini grant | Seeking optimal treatment strategies for malaria infection | |
| Christopher | Burba | NSU | 2009 | equipment grant | Acquisition of an FT-IR Spectrometer at NSU | |
| Stephen | Fields | ECU | 2009 | equipment grant | An inverted epifluorescence microscope for characterization of C. elegans neurons in cell culture | |
| Andrea | Holgado | SWOSU | 2009 | equipment grant | Major research instrumentation : acquisition of a digital inverted flourescent compuound microscope | |
| Hui | Tan | CU | 2009 | equipment grant | Purification and Crystalization of SSK1 protein from Candida albicans | |
| Kenneth | Andrews | ECU | 2009 | equipment grant | Small equipment grant application for tissue processor and microtome | |
| Yuhao | Jiang | UCO | 2009 | collaborative grant | Quantitative Image Analysis for in vivo Trans-rectal Ultrasound-coupled Optical Tomography of the Prostate | |
| Morshed | Khandaker | UCO | 2009 | collaborative grant | Nanoscale Fracture Toughness Measurement of Bone and Nanocomposite Interfaces | |
| Morshed | Khandaker | UCO | 2009 | release time | grant writing | Augmentation of Engineered Tissue Constructs Interfaces using Nanoparticles |
| Yuhao | Jiang | UCO | 2009 | release time | grant writing | Model based Perceptual Optimization of X-Ray Fluoroscopy System” |
| Wei | Chen | UCO | 2009 | release time | grant writing | A Novel Treatment Modality for Metastatic Tumors Using Photothermal Interaction and Immunological Stimulation |
| Evan | Lemley | UCO | 2009 | release time | grant writing | Investigation of the Blood Vessel Geometry and Properties to Fluid Flow Near Vessel Anomalies |
| Jeremy | Thibodeaux | UCO | 2009 | release time | course development | Development of a Biological Calculus Course |
| Tracy | Morris | UCO | 2009 | release time | grant writing | Statistics and Biology Collaboratory |
| Nancy | Paiva | SE | 2009 | release time | course development | Introduction to Mass Spectroscopy of small Molecules |
| Karla | Oty | CU | 2010 | release time | course development | Developing Interdisciplinary Biomedical Projects |
| Diane | Dixon | SE | 2010 | release time | course development | Developing Interdisciplinary Biomedical Projects |
| Brett | Elliott | SE | 2010 | release time | course development | Developing Interdisciplinary Biomedical Projects |
| Alaeddin | AubAbed | UCO | 2010 | release time | grant writing | Developing Nanoplasmonics-Based Biosensor Utilizing Liquid Crystals |
| Joseph | Ahlandar | NSU | 2010 | collaborative grant | Developing an in vivo Model of the Human Papillomavirus E5 Oncogene Using Drosophila Melanogaster as a Model Organism | |
| Wei | Chen | UCO | 2010 | collaborative grant | Enhancing Laer Immunotherapy for Treatment of Metastatic Tumors by Reducing TGF-beta Levels in Tumor Microenvironment | |
| Mohamed | Chehbouni | SE | 2010 | collaborative grant | Phosphate Removal from Hemodialysis Patient Using Magnetic Nanoparticles | |
| Melville | Vaughan | UCO | 2010 | collaborative grant | Environmental Contribution to the Epithelial to Mesenchymal Transition of Ras-overexpressing Keratinocytes in vitro | |
| Hari | Koturi | UCO | 2010 | mini grant | Effect of Bitter Melon leaf extract on mdr1 Gene Expression and Function of P-gp Protein in Drug-Resistant Colon Cancer Cells | |
| Jason | Johnson | SWOSU | 2010 | mini grant | Allosteric Mechanisms of Synchronization within the Triad Glutamine Admidotransferases | |
| Stephen | Fields | SE | 2010 | mini grant | Effects of Melatonin Receptors on Neuronal Development and Behavior | |
| Yahoa | Jiang | UCO | 2010 | mini grant | Quantative Ultrasound Image Processing for Characterization of Cell-Morphology Correlated Optical Properties of Prostate Cancer | |
| Cornelia | Mihai | NWOSU | 2010 | mini grant | Synthesis of Several L-glutamates Derivatives Modified at the Aromatic Ring, as Precursors of New Dihydrofolate Reductase Substrate Analogs | |
| Sharon | Lewis | LU | 2010 | mini grant | Analysis of the Molecular Role of ANK3 in Bipolar Disorder | |
| Daniel | Endres | UCO | 2010 | mini grant | Advanced Stochastic Models for DNA Microsatellite Somatic Instability | |
| Lillian | Chooback | UCO | 2010 | mini grant | Cloning and Characterization of Yeast Aminotransferase | |
| Nancy | Paiva | SE | 2010 | mini grant | Analysis of Phytochemicals in a Traditional Herbal Remedy for BPH | |
| Stephen | Fields | ECU | 2010 | equipment grant | An Incubating Shaker for Cell and Tissue Culture | |
| Diana | Katz | UCO | 2010 | equipment grant | Collection, Isolation and Characteization of Halophilic Organisms and Their Halocins from White Sands National Monument, NM, USA | |
| Morshed | Khandaker | UCO | 2010 | equipment grant | Experimental and Numerical Testing of an Elastomer-type Prosthetic Disc | |
| Lyman | Hawkins | NSU | 2010 | equipment grant | Endoscopic Laryngeal and Acoustic Evaluation of Female Cheerleaders pre-and post-vocal hygiene Training | |
| Andrea | Holgado | SWOSU | 2010 | equipment grant | Expanding Our Tools for Genome-wide Analysis | |
| Robert | Brennan | UCO | 2011 | collaborative grant | Staphylococcus aureus biofilms and chronic wound pathogenesis | |
| Alaeddin | Abu-Abed | UCO | 2011 | mini grant | A novel blood shear stress sensing technique using liquid crystal based capacitive sensor | |
| Jason | Johnson | SWOSU | 2011 | mini grant | Allosteric coordination of glutaminase activity and ammonia tunneling in CTP synthetase | |
| Melville | Vaughan | UCO | 2011 | mini grant | Development of an experimental model to study myofibroblast effect on tumorigenesis | |
| Lilian | Chooback | UCO | 2011 | mini grant | Mechanistic studies of dihydrodipicolinate synthase | |
| Teresa | Golden | SE | 2011 | mini grant | The role of protein phosphatase 5 (PP%) in cancer cell survival | |
| Lilian | Chooback | UCO | 2011 | equipment grant | Mechanistic studies of dihydrodipicolinate synthase | |
| Joseph | Ahlander | NSU | 2011 | equipment grant | Biochemical and phenotypic characterization of Ard1 in drosophila | |
| Wei | Chen | UCO | 2011 | equipment grant | Mechanistic studies of a laser-nanotechnology-based novel therapy for cancer | |
| Christopher | Burba | NSU | 2011 | equipment grant | Acquisition of a Powder X-ray diffractometer at NSU | |
| Melville | Vaughan | UCO | 2011 | release time | grant writing | The growth arrest component of myofibroblast differentiation |
| Tracy | Morris | UCO | 2010 | release time | grant writing | Statistical consulting help for organizational leaders and academic researchers (SCHOLAR) |
| Wei | Chen | UCO | 2011 | release time | grant writing | Nanotube as a carrier of immunoasdju8vant for cellular thermal and immunological interactions for tumor treatment under NIR light irradiation |
| Tim | Hubin | SWOSU | 2011 | release time | grant writing | Synthesis and evaluation of transition metal complex dual CXCR4/CCR5 antagonists |
| Morshed | Khandaker | UCO | 2011 | release time | course development | ENGR 3413 Material Science |
| Lillian | Chooback | UCO | 2011 | release time | grant writing | Mechanistic studies of dihydrodipicolinate synthase |
| Alaeddin | Abu-Abed | UCO | 2011 | release time | course development | ENGR 4910 - Biophotonics |
| Stephen | Fields | ECU | 2011 | release time | course development | Responsible conduct of research |
| Cindy | Cisar | NSU | 2011 | release time | Development fo reservoirs of antibiotic resistance in the environment |